Many foundries like to give you an option to license a font in different formats and customers always ask which format is better. The answer is that your decision should be based on the programs that you will be using the fonts in.
OpenType (.otf) fonts typically have additional features that can only be accessed by programs that support them. OpenType works best in software like Adobe® Illustrator® and Adobe® InDesign®.
Although Microsoft Word 2010 supports some OpenType features, not all characters can be accessed if the font has a massive amount of alternates. For example, trying to access all the alternate swashes in Feel Script in PowerPoint would be painful. Don’t do it.
Also, you’ll only be disappointed further because OpenType fonts don’t embed well in PowerPoint.
If your workflow includes Microsoft Office programs, like Excel and Powerpoint, then we recommend licensing TrueType formats over OpenType. And if the font doesn’t have a TrueType version, contact us and we can suggest an alternate typeface that may work for you.